According to statistics, the incidence of lymphoma in the United States is increasing at an annual rate of 4% for men and 3% for women. The reasons for the increase may be related to viral infections, radiation pollution, solvents, fuels, etc. Among them, many studies are Correlation with viral infection.
Classification of malignant lymphomaMalignant lymphoma is a very heterogeneous cancer. Although it commonly occurs in lymph nodes, due to the special distribution of the lymph node system, malignant lymphoma becomes a systemic disease. As mentioned earlier, it can invade almost any part of the body. Tissues and organs.
Among them, non-Hodgkin's lymphoma can be divided into lymphoid lymphoma and extralymphatic lymphoma according to the location of occurrence. As the name suggests, lymphatic lymphoma is a lymphoma that occurs in lymph glands, such as the neck, armpits, groin, Lymph glands in the mediastinum or abdominal cavity.
Extralymph gland lymphoma occurs in non-lymph gland lymphoid tissues such as spleen, gastrointestinal tract, lung, liver, bone marrow, brain, nasopharynx, skin, thyroid and other parts.
If classified based on cell morphology, immunity, molecular genetics and clinical manifestations, non-Hodgkin's lymphoma can be divided into two categories: B cells and T cells.
Among B-cell lymphomas, diffuse large cell lymphoma and follicular lymphoma are the most common, accounting for 60% to 70% of all lymphomas. The incidence of T-cell lymphoma is lower than that of B-cell lymphoma, among which peripheral T-cell lymphoma is the most common. Cellular lymphoma is the most common, accounting for approximately 7% of all lymphomas.
lymphoma treatmentTreatment methods for non-Hodgkin lymphoma vary due to different cell malignancies, morphological diversity, and stages. In principle, they include radiotherapy, chemotherapy, high-dose chemotherapy combined with hematopoietic stem cell transplantation, etc. Surgery is mostly used for It is initially used when confirming the diagnosis or when internal organs are perforated.
Among them, radiotherapy is a local treatment and can be used to treat lymphomas with low malignancy and low stage. It can also be combined with chemotherapy to treat lymphoma with medium to high malignancy and low stage. In addition, radiotherapy can be used in time when the central nervous system is invaded. Local symptom relief also plays an important role.
Chemotherapy is an extremely important part of the treatment of lymphoma, because lymphoma patients in China often have a higher stage of onset, and the proportion of medium to high malignancy is also high. Therefore, almost all lymphoma patients have undergone chemotherapy.
As for the survival rate of lymphoma, although low-malignancy lymphoma is not easy to cure, the five-year survival rate is still 70%. However, medium- and high-malignancy lymphoma is more aggressive and the survival rate decreases with the increase of stage. However, for Chemotherapy responds well, so about 40% of patients can achieve long-term survival after treatment.